ChlorMezanone (Trancopal)
chlormezanone
CAS: 80-77-3
Molecular Formula: C11H12ClNO3S
ChlorMezanone (Trancopal) - Names and Identifiers
ChlorMezanone (Trancopal) - Physico-chemical Properties
| Molecular Formula | C11H12ClNO3S |
| Molar Mass | 273.74 |
| Density | 1.2205 (rough estimate) |
| Melting Point | 114 °C |
| Boling Point | 534.5±50.0 °C(Predicted) |
| Flash Point | 277.1°C |
| Solubility | DMSO 55 mg/mL;Water <1 mg/mL;Ethanol 26 mg/mL. Slightly soluble in water or ethanol, easily soluble in acetone, chloroform, insoluble in benzene. |
| Vapor Presure | 1.68E-11mmHg at 25°C |
| Appearance | White crystalline powder |
| Color | White to Pale Yellow |
| Merck | 14,2106 |
| pKa | -2.37±0.40(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.6300 (estimate) |
| MDL | MFCD00143951 |
| Physical and Chemical Properties | White crystalline powder. Melting point 116.2-118.2 °c. Slightly soluble in water or ethanol, soluble in acetone, chloroform, insoluble in benzene. Slightly odorous. Decomposition upon heating in an inorganic acid or base. |
| Use | Weak tranquilizer, used for nervous tension fear, chronic fatigue, Anxiety, excitement and irritability caused by certain diseases such as insomnia |
| In vivo study | Comparative results obtained with Chlormezanone in the dosage levels capable of producing more than 80% depression in the contralateral extensor. |
ChlorMezanone (Trancopal) - Risk and Safety
| RTECS | XJ1050000 |
ChlorMezanone (Trancopal) - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| biological activity | Chlormezanone is a non-benzodiazepine for the treatment of anxiety disorders. It has been suggested for the treatment of muscle spasms. |
| Target | Benzodiazepine |
| Use | is used as a weak neuroleptic. With sedation, stability and central muscle relaxation effect. Can also be used for nervous fear, chronic fatigue, Anxiety, excitement, and certain diseases caused by irritability and insomnia. Because of muscle relaxation, with analgesics can be used for back acid, hard neck, bone pain, spine and limbs pain and rheumatism Arthralgia. A weak neuroleptic, used for nervousness, fear, chronic fatigue, Anxiety, agitation and irritability caused by certain diseases such as insomnia |
| production method | from p-chlorobenzaldehyde by condensation with methylamine solution, mercaptopropionic acid cyclization, potassium permanganate solution oxidation. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 21:54:55
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View History
ChlorMezanone (Trancopal)
2-甲基-5-(2-苯基乙基)-1,3-苯二酚
5-甲基吡唑并[1,5-A]吡啶-3-羧酸乙酯
2-Propenoic acid, 2-methyl-, 2-hydroxymethylethyl ester, reaction products with 4,4'-(1-methylethylidene)bis[cyclohexanol] and TDI
(Η5-C5ME5)2NBH(CH2=CH2)
2-AMINO-4-CHLOROBENZOIC ACID
POLYTETRAMETHYLENE OXIDE DI-P-AMINOBENZOATE
NAPHTHALENE-1-CARBOXAMIDINE HYDROCHLORIDE
(2,6-二甲基哌啶-1-基)乙酸盐酸盐
三(2,2,2-三氟乙基)硼酸
2-甲基-5-(2-苯基乙基)-1,3-苯二酚
5-甲基吡唑并[1,5-A]吡啶-3-羧酸乙酯
2-Propenoic acid, 2-methyl-, 2-hydroxymethylethyl ester, reaction products with 4,4'-(1-methylethylidene)bis[cyclohexanol] and TDI
(Η5-C5ME5)2NBH(CH2=CH2)
2-AMINO-4-CHLOROBENZOIC ACID
POLYTETRAMETHYLENE OXIDE DI-P-AMINOBENZOATE
NAPHTHALENE-1-CARBOXAMIDINE HYDROCHLORIDE
(2,6-二甲基哌啶-1-基)乙酸盐酸盐
三(2,2,2-三氟乙基)硼酸